Location: semantic-annotation @ f42c82f77870 / GI Model / SGLT1.cellml

Author:
Dewan Sarwar <sarwarcse@gmail.com>
Date:
2019-01-22 15:53:48+13:00
Desc:
adding the removed namepsaces
Permanent Source URI:
http://models.cellml.org/workspace/584/rawfile/f42c82f77870f412e1964b9b0701fec331344c8d/GI Model/SGLT1.cellml

<?xml version="1.0" encoding="UTF-8"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqs="http://www.cellml.org/bqs/1.0#" xmlns:semsim="http://www.bhi.washington.edu/SemSim#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" name="SGLT1" cmeta:id="SGLT1">
  <units name="mM">
    <unit prefix="milli" units="mole" />
    <unit exponent="-1.0" units="litre" />
  </units>
  <units name="millisec">
    <unit prefix="milli" units="second" />
  </units>
  <units name="flux">
    <unit prefix="milli" units="mole" />
    <unit exponent="-1.0" units="second" />
    <unit exponent="-3.0" prefix="centi" units="metre" />
  </units>
  <units name="per_millisec">
    <unit exponent="-1.0" prefix="milli" units="second" />
  </units>
  <component name="environment">
    <variable cmeta:id="environment.time" name="time" public_interface="out" units="second" />
  </component>
  <component name="SGLT1">
    <variable cmeta:id="SGLT1.C_lumen_Na" name="C_lumen_Na" public_interface="in" units="mM" />
    <variable cmeta:id="SGLT1.C_int_Na" name="C_int_Na" public_interface="in" units="mM" />
    <variable cmeta:id="SGLT1.C_lumen_glucose" name="C_lumen_glucose" public_interface="in" units="mM" />
    <variable cmeta:id="SGLT1.C_int_glucose" name="C_int_glucose" public_interface="in" units="mM" />
    <variable cmeta:id="SGLT1.J_Na" name="J_Na" public_interface="in" units="flux" />
    <variable cmeta:id="SGLT1.J_Glucose" name="J_Glucose" public_interface="in" units="flux" />
  </component>
  <rdf:RDF xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" xmlns:opb="http://bhi.washington.edu/OPB#">
    <rdf:Description rdf:about="">
      <dc:title>HH sodium ion channel model</dc:title>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1">
      <ro:modelOf rdf:resource="http://purl.obolibrary.org/obo/PR_P53790" />
      <ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_17721" />
      <ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_66836" />
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.C_tissue_Cl">
      <dcterms:description>concentration of chloride in the tissue fluid compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1" semsim:modelId="SGLT1" semsim:modelName="SGLT1" />
    <rdf:Description rdf:about="#SGLT1.C_tissue_Na">
      <dcterms:description>concentration of sodium in the tissue fluid compatrment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.C_int_Na">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_1">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#entity_2">
              <ro:part_of>
                <rdf:Description rdf:about="#entity_3">
                  <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_66836" />
                </rdf:Description>
              </ro:part_of>
              <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101" />
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>concentration of sodium in the cytosol compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#process_0" dcterms:description="" />
    <rdf:Description rdf:about="#SGLT1.J_Cl">
      <dcterms:description>Flux of chloride from tissue fluid to cytosol compartment through NKCC and basolateral membrane</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.C_lumen_glucose">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_2">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#entity_4">
              <ro:part_of>
                <rdf:Description rdf:about="#entity_1">
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                </rdf:Description>
              </ro:part_of>
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            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>concentration of glucose in the luminal compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.C_tissue_K">
      <dcterms:description>concentration of potassium in the tissue fluid compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#environment.time" dcterms:description="Time">
      <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_01023" />
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.J_K">
      <dcterms:description>Flux of potasium from tissue fluid to cytosol compartment through NKCC and basolateral membrane</dcterms:description>
      <dcterms:description>Flux of potassium from tissue fluid to cytosol compartment through NKCC and basolateral membrane</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.C_lumen_Na">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_0">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#entity_0">
              <ro:part_of rdf:resource="#entity_1" />
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            </rdf:Description>
          </semsim:physicalPropertyOf>
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        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>concentration of sodium in the luminal compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#process_2" dcterms:description="" />
    <rdf:Description rdf:about="#SGLT1.C_int_K">
      <dcterms:description>concentration of potassium in the cytosol compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#model">
      <bqs:reference rdf:parseType="Resource">
        <dc:subject rdf:parseType="Resource">
          <bqs:subject_type>keyword</bqs:subject_type>
          <rdf:value>
            <rdf:Bag>
              <rdf:li>protein module</rdf:li>
            </rdf:Bag>
          </rdf:value>
        </dc:subject>
      </bqs:reference>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.J_Na">
      <dcterms:description>Flux of sodium from tissue fluid to cytosol compartment through NKCC and basolateral membrane</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.J_Na">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_4">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#process_0" dcterms:description="">
              <semsim:hasMediatorParticipant>
                <rdf:Description rdf:about="#mediator_1">
                  <semsim:hasPhysicalEntityReference>
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                </rdf:Description>
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              <semsim:hasMediatorParticipant>
                <rdf:Description rdf:about="#mediator_0">
                  <semsim:hasPhysicalEntityReference>
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                  </semsim:hasPhysicalEntityReference>
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              <semsim:hasSinkParticipant>
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                  <semsim:hasPhysicalEntityReference rdf:resource="#entity_2" />
                </rdf:Description>
              </semsim:hasSinkParticipant>
              <semsim:hasSourceParticipant>
                <rdf:Description rdf:about="#source_0" semsim:hasMultiplier="1.0">
                  <semsim:hasPhysicalEntityReference rdf:resource="#entity_0" />
                </rdf:Description>
              </semsim:hasSourceParticipant>
              <semsim:name>Na flow from luminal to cytosol</semsim:name>
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00593" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>Flux of sodium from luminal to cytosol through SGLT1 and apical membrane</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#process_1" dcterms:description="" />
    <rdf:Description rdf:about="#SGLT1.C_int_glucose">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_3">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#entity_5">
              <ro:part_of rdf:resource="#entity_3" />
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            </rdf:Description>
          </semsim:physicalPropertyOf>
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        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>concentration of glucose in the cytosol compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.J_Glucose">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_5">
          <semsim:physicalPropertyOf>
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                </rdf:Description>
              </semsim:hasMediatorParticipant>
              <semsim:hasMediatorParticipant>
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                  <semsim:hasPhysicalEntityReference rdf:resource="#entity_6" />
                </rdf:Description>
              </semsim:hasMediatorParticipant>
              <semsim:hasSinkParticipant>
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                  <semsim:hasPhysicalEntityReference rdf:resource="#entity_5" />
                </rdf:Description>
              </semsim:hasSinkParticipant>
              <semsim:hasSourceParticipant>
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                  <semsim:hasPhysicalEntityReference rdf:resource="#entity_4" />
                </rdf:Description>
              </semsim:hasSourceParticipant>
              <semsim:name>glucose flow from luminal to cytosol</semsim:name>
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00593" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>Flux of glucose from luminal to cytosol through SGLT1 and apical membrane</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.C_int_Na">
      <dcterms:description>concentration of sodium in the cytosol compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#SGLT1.C_int_Cl">
      <dcterms:description>concentration of chloride in the cytosol compartment</dcterms:description>
    </rdf:Description>
  </rdf:RDF>
</model>